Research Article
Intracranial Biodegradable Silica-Based Nimodipine Drug Release Implant for Treating Vasospasm in Subarachnoid Hemorrhage in an Experimental Healthy Pig and Dog Model
Figure 5
Cumulative degradation of silica (▪) and release of nimodipine (●) from implant B dissolution medium (50 mM Tris buffer, pH = 7.4 at 37°C) in flow-through dissolution. Flow rate of the dissolution medium was 500 mL/day.