Design, Materials, and Mechanobiology of Biodegradable Scaffolds for Bone Tissue Engineering

Table 3

Porous biocomposites used for bone tissue engineering. From Chen et al. [142] and Wahl and Czernuszka [143].

Biocomposite		Percentage of ceramic (wt.%)	Porosity (%)	Pore size (m)	Strength (MPa)	Modulus (MPa)	Ultimate strain (%)
Amorphous CaP	PLGA	28 to 75	75	>100		65
β-TCP	Chitosan-gelatin	10 to 70		322 to 355	0.32 to 0.88	3.94 to 10.88
HA	PLLA	50	85 to 96	100 × 300	0.39	10 to 14
	PLGA	60 to 75	81 to 91	800 to 1800	0.07 to 0.22	2 to 7.5
	PLGA		30 to 40	110 to 150		337 to 1459
	Collagen	Variable	~0	~0	34–60	0.44–2.82
	PLG	75	43	89	0.42	51
Bioglass	PLLA	20 to 50	77 to 80	Approximately 100 (macro); approximately 10 (micro)	1.5 to 3.9	137 to 260	1.1 to 13.7
	PLG	0.1 to 1		50 to 300
	PDLLA	5 to 29	94	Approximately 100 (macro); 10 to 50 (micro)	0.07 to 0.08	0.65 to 1.2	7.21 to 13.3
Phosphate glass A/W	PLA-PDLLA	40	93 to 97	98 to 154	0.017 to 0.020	0.075 to 0.12
	PDLLA	20 to 40	85.5 to 95.2
Bioglass	PGS	90	>90	300 to 500	0.4 to 1.0