Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Figure 1

Heatmap showing Spearman correlation values computed for all expressed genes and all 30 samples sequences for this study. The histogram on top left denotes the distribution of the correlation values as well as the colors for each value. The dendrograms on top and left of the histogram are identical but show different colors at their leaves: top: color denotes the cell line (blue: HFF; red: MRC-5); left: color denotes the PD (bright to dark → young to old). Samples are clustered first according to cell line and second according to PD. Highest correlations were found between the three replicates (light areas on the main diagonal).