Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Figure 9

Functional association network by GeneMANIA for 23 monotonically up- or downregulated genes. Input genes are depicted by either black, red, or blue color or large circles. Intermediate genes, added by the tool, are shown using small grey circles. Colored genes denote functions associated by the tools: blue = “epithelial cell proliferation”; red = “ extracellular matrix organization.” The edge colors indicate the type of interaction, as explained in the legend on the bottom right.