MicroRNA Clusters in the Adult Mouse Heart: Age-Associated Changes

Table 1

The number of mouse miRNAs and miRNA clusters distributed on each chromosome. A total of 1193 miRNAs were observed in the mouse miRBase database release version 21. Six miRNAs were not assigned to any of the chromosomes. Various inter-miRNA distances (1 Kb, 2 Kb, 3 Kb, 5 Kb, and 10 Kb) were used in an effort to define the potential miRNA clusters. Approximately 25% of the miRNA clusters are located within a 2 Kb distance.

Chromosome	Total miRs	Cluster number
		<10 Kb	<5 Kb	<3 Kb	<2 Kb	<1 Kb
1	61	12	8	6	6	6
2	147	90	88	88	86	83
3	46	9	9	9	9	9
4	56	8	8	8	7	7
5	54	5	5	5	3	3
6	43	11	11	10	10	10
7	85	19	16	15	11	11
8	57	12	8	8	8	8
9	50	8	6	6	6	4
10	52	6	4	4	2	2
11	86	18	16	16	16	14
12	94	60	56	55	55	47
13	33	10	10	10	10	8
14	42	10	10	10	10	10
15	48	6	6	4	4	4
16	34	8	8	6	6	6
17	40	15	9	7	5	5
18	32	7	7	5	4	2
19	36	2	2	2	2	2
	91	56	56	47	42	34
Other^*	6
Cluster number		94	87	84	81	93
Total miRs	1193	372	343	321	302	275
Cluster %		31%	29%	27%	25%	23%

Six miRNAs have not been localized into any of the above chromosome.