The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice

<div>Representative hearts and H&amp;E and Masson’s trichrome-stained LV and RV sections from R21C<sup>+/+</sup> and WT mice. LV and RV sections from the hearts of ~7-month-old male R21C<sup>+/+</sup> and WT mice were imaged. Note: no mutation-induced abnormalities in H&amp;E stained sections from the hearts of R21C<sup>+/+</sup> compared with WT mice. Very mild histopathological changes could infrequently be observed in Masson’s trichrome-stained LV sections from R21C<sup>+/+</sup> mice.</div>

BioMed Research International

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Figure 1

Figure 1: The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice 

Figure 1 | The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice 