Evaluation of the Efficacy of a Bacteriophage in the Treatment of Pneumonia Induced by Multidrug Resistance Klebsiella pneumoniae in Mice

Figure 3

(a) Phage 1513’s one-step growth curve was measured. Bacteriophages showed a latent period of about 30 min and a burst size of 264 PFU mL⁻¹. (b) Lytic ability of phage 1513 in vitro. KP (2 × 10⁹ CFU mL⁻¹) was infected with the phage at different multiplicities of infection (MOI). The optical density at 650 nm was determined at each timepoint. Infection dose of phage: none (▲), 2 × 10¹⁰ PFU mL⁻¹ (▼), 2 × 10⁹ PFU mL⁻¹ (●), and 2 × 10⁸ PFU mL⁻¹ (■).

(a)

(b)