Effects of Caloric Intake on Learning and Memory Function in Juvenile C57BL/6J Mice

Figure 3

Expression of SIRT1 pathway regulators. The mRNA expression of SIRT1 in hippocampal and cortical tissues of mice examined by RT-PCR (a). The protein expressions of SIRT1, p53, p16, and PPARγ assessed with Western blot (b) and immunohistochemistry (c), respectively. Magnification: 400. The number of immunopositive neurons per area in hippocampal CA1 region was counted (d). compared with control; compared with LC. for each group.

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