Review Article

Diagnosis and Management of Iridocorneal Endothelial Syndrome

Table 1

Clinical features of the different ICE syndrome subtypes.

ā€‰IrisPupilCorneaAnterior chamber angle

Chandler syndromeAreas of atrophy
(not full-thickness holes)
CorectopiaEarly and marked edema, endothelial dystrophy, and ICE-cells at confocal microscopyPeripheral anterior synechiae

Progressive iris atrophyFull-thickness hole(s)PolycoriaEndothelial dystrophy, ICE-cells at confocal microscopy, and corneal edema may occurPeripheral anterior synechiae

Cogan-Reese syndromeNodules and iris atrophyChanges uncommonEndothelial dystrophy, ICE-cells at confocal microscopy, and corneal edema may occurPeripheral anterior synechiae