Research Article

Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation

Figure 1

PEDF activated p38/MAPK signalling pathway in dose- and time-dependent manner. Representative blots and data summary of phospho-p38 (p-p38) and p38 in HUVECs under PEDF (100/200 ng/mL) treatment at indicated time points. Representative western blots are shown for the two groups. Graph represents the mean ± SD ( in each group) of the relative integrated signals. , .