Significance of Neutrophil Gelatinase-Associated Lipocalin Level-to-Serum Creatinine Ratio for Assessing Severity of Inflammation in Patients with Renal Dysfunction

Table 4

Diagnostic ability of the NGAL/sCr ratio to identify NLR > 4.5 and cESR > 25 mm/h in patients with renal dysfunction, compared with that of NGAL and hsCRP.

	ROC curve analysis
	AUC	95% confidence interval	values
NGAL versus NGAL/sCr ratio
NLR > 4.5
NGAL/sCr ratio	0.674	0.545–0.803	0.016
NGAL	0.623	0.482–0.763	0.048
cESR > 25 mm/h
NGAL/sCr ratio	0.686	0.556–0.817	0.013
NGAL	0.635	0.487–0.785	0.041
hsCRP versus NGAL/sCr ratio
NLR > 4.5
NGAL/sCr ratio	0.729	0.594–0.865	0.002
hsCRP	0.665	0.517–0.815	0.027
cESR > 25 mm/h
NGAL/sCr ratio	0.686	0.560–0.812	0.010
hsCRP	0.674	0.545–0.803	0.016

ROC, receiver operating characteristics; AUC, area under the curve; NGAL, neutrophil gelatinase-associated lipocalin; NGAL/sCr ratio, NGAL-to-serum creatinine ratio; NLR, neutrophil-to-lymphocyte ratio; cESR, corrected erythrocyte sedimentation rate; hsCRP, high sensitivity C-reactive protein.