Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1 as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients

Figure 3

MMPs promoter activity. Plasmid constructs harboring: MMP1 2G: insertion of additional guanine in position -1607 (2G) in MMP1 gene (pGL 4.11 MMP1 2G); MMP9 T: change in position -1562 from C to T in MMP9 gene. pGL 4.11 nc: negative control (promoterless); pGL 4.13: positive control (CMV promoter). Data presented as relative luciferase units RLU calculated as FLA/RLA of the sample. Error bars represent standard deviations (SD). . Data from three independent experiments with independent transfections ().