Research Article

Integrative Analysis with Monte Carlo Cross-Validation Reveals miRNAs Regulating Pathways Cross-Talk in Aggressive Breast Cancer

Table 1

Pathways enriched from differentially expressed genes.

Pathway FDR Number of genes in pathway Number of common genes

Agranulocyte Adhesion and Diapedesis FDR = (ng = 173) (nc = 62)
Atherosclerosis Signaling FDR = (ng = 119) (nc = 44)
Granulocyte Adhesion and Diapedesis FDR = (ng = 163) (nc = 53)
LXR/RXR Activation FDR = (ng = 121) (nc = 42)
Inhibition of Matrix Metalloproteases FDR = (ng = 38) (nc = 19)
Hepatic Fibrosis/Hepatic Stellate Cell Activation FDR = (ng = 137) (nc = 44)
Acute Phase Response Signaling FDR = (ng = 167) (nc = 49)
ILK Signaling FDR = (ng = 181) (nc = 52)
Ethanol Degradation II FDR = (ng = 30) (nc = 15)
Intrinsic Prothrombin Activation Pathway FDR = (ng = 28) (nc = 14)
Coagulation System FDR = (ng = 35) (nc = 16)
Extrinsic Prothrombin Activation Pathway FDR = (ng = 16) (nc = 10)
Noradrenaline and Adrenaline Degradation FDR = (ng = 32) (nc = 15)
Bladder Cancer Signaling FDR = (ng = 86) (nc = 29)
Axonal Guidance Signaling FDR = (ng = 421) (nc = 98)
Ethanol Degradation IV FDR = (ng = 17) (nc = 10)
Colorectal Cancer Metastasis Signaling FDR = (ng = 232) (nc = 60)
Wnt/_-catenin Signaling FDR = (ng = 167) (nc = 46)
Cardiac_-adrenergic Signaling FDR = (ng = 132) (nc = 38)
Protein Kinase A Signaling FDR = (ng = 365) (nc = 84)
LPS/IL-1 Mediated Inhibition of RXR Function FDR = (ng = 210) (nc = 52)
EIF2 Signaling FDR = (ng = 171) (nc = 11)
Epithelial Adherens Junction Signaling FDR = (ng = 144) (nc = 38)
HIF1_Signaling FDR = (ng = 100) (nc = 29)
Oxidative Ethanol Degradation III FDR = 3 (ng = 15) (nc = 8)
Retinoate Biosynthesis I FDR = (ng = 29) (nc = 12)
Factors Promoting Cardiogenesis in Vertebrates FDR = (ng = 87) (nc = 26)
GADD45 Signaling FDR = (ng = 19) (nc = 9)
Mitotic Roles of Polo-Like Kinase FDR = (ng = 62) (nc = 20)
TR/RXR Activation FDR = (ng = 85) (nc = 25)
Aryl Hydrocarbon Receptor Signaling FDR = (ng = 133) (nc = 35)
Role of Osteoblasts, Osteoclasts FDR = (ng = 214) (nc = 50)
Estrogen-mediated S-phase Entry FDR = (ng = 24) (nc = 10)
Calcium Signaling FDR = (ng = 168) (nc = 41)
Estrogen Receptor Signaling FDR = (ng = 126) (nc = 8)
Triacylglycerol Biosynthesis FDR = (ng = 33) (nc = 12)
Mitochondrial Dysfunction FDR = (ng = 139) (nc = 10)
Thyroid Cancer Signaling FDR = (ng = 40) (nc = 14)
Human Embryonic Stem Cell Pluripotency FDR = (ng = 132) (nc = 34)
FXR/RXR Activation FDR = (ng = 82) (nc = 22)
Glycogen Degradation II FDR = (ng = 9) (nc = 5)
Putrescine Degradation III FDR = (ng = 16) (nc = 7)
Tryptophan Degradation X FDR = (ng = 16) (nc = 7)
Dopamine Degradation FDR = (ng = 21) (nc = 8)
Glioma Invasiveness Signaling FDR = (ng = 57) (nc = 17)
Actin Cytoskeleton Signaling FDR = (ng = 210) (nc = 47)
NAD biosynthesis II (from tryptophan) FDR = (ng = 13) (nc = 6)
Fatty Acid_-oxidation FDR = (ng = 13) (nc = 6)