Research Article
Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility
Figure 2
Association between rs2872507 genotype and intestinal GSDMB expression in IBD patients. Genotype (A is the IBD risk allele) versus the relative quantity (RQ) of GSDMB expression in intestinal biopsies from noninflamed ileal IBD mucosa ((a) = 4, = 14, = 6; = −0.61, = 1.54 × 10−3), noninflamed colonic IBD mucosa ((b) = 8, = 14, = 7; = −0.87, = 7.18 × 10−10), and inflamed colonic IBD mucosa ((c) = 9, = 12, = 7; = −0.53, = 4.12 × 10−3).
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