Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility

Figure 3

Association between rs2872507 genotype and ileal PGAP3 expression in IBD patients. Genotype (A is the IBD risk allele) versus the relative quantity (RQ) of PGAP3 expression in intestinal biopsies from noninflamed ileal IBD mucosa ((a) = 4, = 14, = 6; = −0.60, = 2.00 × 10⁻³) or the RQ of ZPBP2 expression in noninflamed ileal CD mucosa ((b) = 1, = 6, = 4; = −0.86, = 7.68 × 10⁻⁴).

(a)

(b)