Verification of the Chromosome Region 9q21 Association with Pelvic Organ Prolapse Using RegulomeDB Annotations

Figure 1

Gene-gene interaction plot. The plot shows the significance levels of gene-gene interactions and pelvic organ prolapse (POP) in the dominant model. Each plot indicated the values preceded by different likelihood ratio tests. Different colors show different levels of statistical significance. The diagonal line contains the values from likelihood ratio test for the crude effect of each SNP. The upper triangle in the matrix presents the values for the interaction (epistasis) log-likelihood ratio test. The lower triangle shows the values from likelihood ratio test comparing the two-SNP additive likelihood to the best of the single-SNP models.