Tyrosine 705 Phosphorylation of STAT3 Is Associated with Phenotype Severity in TGFβ1 Transgenic Mice

Figure 1

STAT3 phosphorylation level following TGFβ1 overexpression. Representative western blot of vastus lateralis muscle protein samples of controls (), LO (), and EO (), with anti-phopsho-STAT3 (Tyr705), anti-phospho-STAT3 (Ser727), anti-total-STAT3, and anti-GAPDH. Graphs show normalized expression values of pSTAT3 (Tyr705), pSTAT3 (Ser727), and total STAT3 normalized to GAPDH ± SEM. All the values are normalized for the average of the control. indicates .