Biomechanical Stability of Dental Implants in Augmented Maxillary Sites: Results of a Randomized Clinical Study with Four Different Biomaterials and PRF and a Biological View on Guided Bone Regeneration

Table 2

Cumulative statistical evaluation of ITVs obtained in the subperiosteal-tunnel-technique (SP) study and INTRALIFT (IL) study by a one-way ANOVA test, Student’s -test, and post hoc multiple comparisons by Fisher’s least significant difference (LSD) to test mean insertion-torque-values and variance in each group and mean difference significance between all groups.

(a)

Means comparisons
Comparisons for each pair using Student's
Confidence quantile
	Alpha
1.9674	0.05

(b)

LSD threshold matrix
Abs(Dif)-LSD
	Easy-graft CRYSTAL_IL	Easy-graft CRYSTAL_SP	Easy-graft CLASSIC + PRF_SP	Easy-graft CLASSIC_IL	Easy-graft CLASSIC_SP	Nanobone_IL	Control Group Native Bone Front-Canine_SP	BioOss_IL	Control Group Native Bone premolar-molar_IL
Easy-graft CRYSTAL_IL	−2.53	1.51	7.15	8.24	11.48	20.80	26.02	27.77	31.88
Easy-graft CRYSTAL_SP	1.51	−2.60	3.04	4.12	7.36	16.68	21.90	23.65	27.76
Easy-graft CLASSIC + PRF_SP	7.15	3.04	−2.53	−1.45	1.79	11.11	16.33	18.08	22.19
Easy-graft CLASSIC_IL	8.24	4.12	−1.45	−2.44	0.80	10.12	15.33	17.09	21.20
Easy-graft CLASSIC_SP	11.48	7.36	1.79	0.80	−2.64	6.68	11.90	13.65	17.76
Nanobone_IL	20.80	16.68	11.11	10.12	6.68	−2.41	2.80	4.56	8.67
ContrGroupNativeBone Front-Canine_SP	26.02	21.90	16.33	15.33	11.90	2.80	−2.85	−1.11	3.00
BioOss_IL	27.77	23.65	18.08	17.09	13.65	4.56	−1.11	−2.68	1.43
ContrGroupNativeBone premol-molar_IL	31.88	27.76	22.19	21.20	17.76	8.67	3.00	1.43	−2.64

Positive values show pairs of means that are significantly different.

(c)

Connecting letters report
Level								Mean
Easy-graft CRYSTAL_IL	A							56.58
Easy-graft CRYSTAL_SP		B						52.50
Easy-graft CLASSIC + PRF_SP			C					46.89
Easy-graft CLASSIC_IL			C					45.85
Easy-graft CLASSIC_SP				D				42.51
Nanobone_IL					E			33.31
ContrGroupNativeBone Front-Canine_SP						F		27.87
BioOss_IL						F		26.21
ContrGroupNativeBone premol-molar_IL							G	22.11

Levels not connected by same letter are significantly different.

(d)

Ordered differences report
Level	compared to	Level	Difference	Std. err. dif.	Lower CL	Upper CL	-value
Easy-graft CRYSTAL_IL		ContrGroupNativeBone premolar-molar_IL	34.46	1.32	31.88	37.05	<0.0001
Easy-graft CRYSTAL_SP		ContrGroupNativeBone premolar-molar_IL	30.39	1.33	27.76	33.01	<0.0001
Easy-graft CRYSTAL_IL		BioOss_IL	30.37	1.33	27.77	32.98	<0.0001
Easy-graft CRYSTAL_IL		ContrGroupNativeBone Front-Canine_SP	28.71	1.37	26.01	31.41	<0.0001
Easy-graft CRYSTAL_SP		BioOss_IL	26.29	1.34	23.65	28.94	<0.0001
Easy-graft CLASSIC + PRF_SP		ContrGroupNativeBone premolar-molar_IL	24.78	1.32	22.19	27.37	<0.0001
Easy-graft CRYSTAL_SP		ContrGroupNativeBone Front-Canine_SP	24.63	1.39	21.90	27.36	<0.0001
Easy-graft CLASSIC_IL		ContrGroupNativeBone premolar-molar_IL	23.74	1.29	21.20	26.28	<0.0001
Easy-graft CRYSTAL_IL		Nanobone_IL	23.27	1.26	20.80	25.74	<0.0001
Easy-graft CLASSIC + PRF_SP		BioOss_IL	20.69	1.33	18.08	23.30	<0.0001
Easy-graft CLASSIC_SP		ContrGroupNativeBone premolar-molar_IL	20.40	1.34	17.76	23.04	<0.0001
Easy-graft CLASSIC_IL		BioOss_IL	19.65	1.30	17.09	22.21	<0.0001
Easy-graft CRYSTAL_SP		Nanobone_IL	19.19	1.28	16.68	21.70	<0.0001
Easy-graft CLASSIC + PRF_SP		ContrGroupNativeBone Front-Canine_SP	19.03	1.37	16.33	21.73	<0.0001
Easy-graft CLASSIC_IL		ContrGroupNativeBone Front-Canine_SP	17.99	1.35	15.33	20.64	<0.0001
Easy-graft CLASSIC_SP		BioOss_IL	16.31	1.35	13.65	18.97	<0.0001
Easy-graft CLASSIC_SP		ContrGroupNativeBone Front-Canine_SP	14.65	1.40	11.90	17.40	<0.0001
Easy-graft CRYSTAL_IL		Easy-graft_CLASSIC_SP	14.06	1.32	11.48	16.65	<0.0001
Easy-graft CLASSIC + PRF_SP		Nanobone_IL	13.59	1.26	11.11	16.06	<0.0001
Easy-graft CLASSIC_IL		Nanobone_IL	12.54	1.23	10.12	14.97	<0.0001
Nanobone_IL		ContrGroupNativeBone premolar-molar_IL	11.20	1.28	8.67	13.72	<0.0001
Easy-graft CRYSTAL_IL		Easy-graft CLASSIC_IL	10.73	1.26	8.24	13.21	<0.0001
Easy-graft CRYSTAL_SP		Easy-graft CLASSIC_SP	9.99	1.33	7.36	12.61	<0.0001
Easy-graft CRYSTAL_IL		Easy-graft CLASSIC + PRF_SP	9.68	1.29	7.15	12.22	<0.0001
Easy-graft CLASSIC_SP		Nanobone_IL	9.20	1.28	6.68	11.73	<0.0001
Nanobone_IL		BioOss_IL	7.10	1.30	4.56	9.65	<0.0001
Easy-graft CRYSTAL_SP		Easy-graft CLASSIC_IL	6.65	1.28	4.12	9.17	<0.0001
ContrGroupNativeBone Front-Canine_SP		ContrGroupNativeBone premolar-molar_IL	5.75	1.40	3.00	8.50	<0.0001
Easy-graft CRYSTAL_SP		Easy-graft CLASSIC + PRF_SP	5.61	1.31	3.04	8.17	<0.0001
Nanobone_IL		ContrGroupNativeBone Front-Canine_SP	5.44	1.34	2.80	8.08	<0.0001
Easy-graft CLASSIC + PRF_SP		Easy-graft CLASSIC_SP	4.38	1.32	1.79	6.97	0.0010
BioOss_IL		ContrGroupNativeBone premolar-molar_IL	4.09	1.35	1.43	6.75	0.0027
Easy-graft CRYSTAL_IL		Easy-graft CRYSTAL_SP	4.08	1.31	1.51	6.65	0.0019
Easy-graft CLASSIC_IL		Easy-graft CLASSIC_SP	3.34	1.29	0.80	5.88	0.0102
ContrGroupNativeBone Front-Canine_SP		BioOss_IL	1.66	1.41	−1.11	4.43	0.2385
Easy-graft CLASSIC + PRF_SP		Easy-graft CLASSIC_IL	1.04	1.26	−1.45	3.53	0.4108