Research Article

Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 10

Distribution of METTL3 and METTL14 targeted RNA methylation sites. For both METTL3 and METTL14, their targeted RNA methylation sites are relatively enriched near stop codon of mRNA; however, compared with METTL14 targets, METTL3 targets are relatively enriched on untranslated regions (5′ and 3′UTR). On lncRNA, their targets are unfirmly distributed with slightly enriched on 5′ end.