Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 7

Boxplot of AUCs for different sequencing depths. The performance of all 3 approaches decreases together with the sequencing depth. FHC strategy gives the best performance and the advantage of FET-HMM over exomePeak is the most prominent when the data is of mediocre sequencing depth.