Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 8

Boxplot of AUCs for different unbalanced sequencing depths. The performance of all 3 approaches decreases as the sequencing depth decreases and FHC strategy outperforms FHB and exomePeak on most settings. In this test, the sequencing depth of IP sample under treated condition varies with that of the other 3 samples unchanged.