Research Article
Effect of the Common Fat Mass and Obesity Associated Gene Variants on Obesity in Pakistani Population: A Case-Control Study
Table 2
Allele/genotype frequencies in obese and control subjects.
| |
SNP |
Allele | Frequency (%) |
Genotype | Frequency (%) | value, OR (CI) | Overall
() | Obese
() | Controls
() | Obese
() | Controls
() |
| | rs9939609 | T
A | 73.4
26.6 | 70.7
29.3 | 76.5
23.5 | TT
TA
AA | 52.9
35.7
11.5 | 57.9
37.1
5.0 | 0.017
2.36 (1.14–4.86) |
| | rs8050136 | C
A | 56.5
43.5 | 52.9
47.1 | 63.6
36.4 | CC
CA
AA | 29.5
46.7
23.8 | 42.1
43.0
14.9 | 0.16
1.78 (1.11–2.85) |
| | rs1121980 | G
A | 68.6
31.4 | 62.5
37.5 | 75.3
24.7 | GG
GA
AA | 38.5
48.0
13.5 | 54.8
41.2
4.1 | 0.0003
3.68 (1.72–7.89) |
| | rs9926289 | G
A | 69.5
30.5 | 64.3
35.7 | 75.1
24.9 | GG
GA
AA | 41.8
45.1
13.1 | 56.6
37.1
6.3 | 0.014
2.23 (1.16–4.30) |
|
|
Legend: OR: odds ratio, CI: confidence interval.
|
