Research Article
Associations of LIG4 and HSPB1 Genetic Polymorphisms with Risk of Radiation-Induced Lung Injury in Lung Cancer Patients Treated with Radiotherapy
Table 1
Patient demographics and baseline disease characteristics.
| | Patients ( = 160) | Ratio (%) |
| Age (years) | 59.0 (25–75) | | Gender | | | Male | 126 | 78.8 | Female | 34 | 21.2 | Smoking status | | | Smoker | 120 | 75.0 | Nonsmoker | 40 | 25.0 | Histological findings | | | Squamous cell carcinoma | 50 | 31.2 | Adenocarcinoma | 40 | 25.0 | Others | 15 | 9.4 | Small cell carcinoma | 55 | 34.4 | Stages of lung cancer | | | I | 5 | 3.1 | II | 10 | 6.2 | II | 110 | 68.8 | IV | 35 | 21.9 | Chemotherapy | | | Yes | 127 | 79.4 | No | 33 | 20.6 | Types of chemotherapy | | | CCRT | 30 | 18.8 | SCRT | 20 | 12.5 | | 110 | 68.7 | GTV (cm3) | 127.54 (13.12–780.36) | | 20 (lung-PTV) (%) | 36 (3–75) | |
|
|
CCRT: concurrent chemoradiotherapy; SCRT: sequential chemoradiotherapy; GTV: gross tumor volume; PTV = planning target volume; 20 = percentage volume of structure receiving dose of 20 Gy or more.
|