Associations of LIG4 and HSPB1 Genetic Polymorphisms with Risk of Radiation-Induced Lung Injury in Lung Cancer Patients Treated with Radiotherapy

Table 2

Univariate analysis of count data for the risk of grade ≥2 radiation pneumonitis after radiation therapy in patients with lung cancer.

Parameter	Variable	Patients ( = 160)	Number of RPs
Gender	Male	126	24	0.640
	Female	34	8
Smoking status	Yes	120	21	0.273
	No	40	11
Histology	NSCLC	105	25	0.167
	SCLC	55	7
Stage	I	5	0	0.292
	II	10	4
	III	110	24
	IV	35	4
Treatment	RT alone	30	6	0.630
	CCRT	20	6
	SCRT	110	20

RP: radiation pneumonitis; NSCLC: non-small cell lung cancer; SCLC: small cell lung cancer; SCRT: sequential chemoradiotherapy; CCRT: concurrent chemoradiotherapy; RT: radiotherapy.