15d-PGJ2 Reduced Microglia Activation and Alleviated Neurological Deficit of Ischemic Reperfusion in Diabetic Rat Model

Table 7

Quantification of infarcted volume of brain lesion and cerebral edema volume.

Group	24 hours after reperfusion		7 days after reperfusion
	Infarcted volume (mm^3)	Cerebral edema volume (mm^3)	Infarcted volume (mm^3)	Cerebral edema volume (mm^3)
Sham-operated group	9.89 ± 1.96	8 ± 2.45	9.53 ± 2.73	7.2 ± 1.42
Standard ischemia group	445.19 ± 78.54^△	34 ± 9.23^△	392.19 ± 53.31	26 ± 8.56^△
Diabetic ischemia group	601.73 ± 120.25	46 ± 15.52	545.73 ± 101.76	38 ± 12.34
Diabetic ischemia group and treated with 15d-PGJ2	386.38 ± 98.22	32 ± 8.50	256.27 ± 67.74	19 ± 6.67

Note: △ indicates value is less than 0.05 when compared with sham-operated group; indicates value is less than 0.05 when compared with standard ischemia group; ▲ indicates value is less than 0.05 when compared with diabetic ischemia group.