15d-PGJ2 Reduced Microglia Activation and Alleviated Neurological Deficit of Ischemic Reperfusion in Diabetic Rat Model
Table 7
Quantification of infarcted volume of brain lesion and cerebral edema volume.
Group
24 hours after reperfusion
7 days after reperfusion
Infarcted volume (mm3)
Cerebral edema volume (mm3)
Infarcted volume (mm3)
Cerebral edema volume (mm3)
Sham-operated group
9.89 ± 1.96
8 ± 2.45
9.53 ± 2.73
7.2 ± 1.42
Standard ischemia group
445.19 ± 78.54△
34 ± 9.23△
392.19 ± 53.31
26 ± 8.56△
Diabetic ischemia group
601.73 ± 120.25
46 ± 15.52
545.73 ± 101.76
38 ± 12.34
Diabetic ischemia group and treated with 15d-PGJ2
386.38 ± 98.22
32 ± 8.50
256.27 ± 67.74
19 ± 6.67
Note: △ indicates value is less than 0.05 when compared with sham-operated group; indicates value is less than 0.05 when compared with standard ischemia group; ▲ indicates value is less than 0.05 when compared with diabetic ischemia group.