Detecting Protein-Protein Interactions with a Novel Matrix-Based Protein Sequence Representation and Support Vector Machines

Table 2

Comparing the prediction performance by the proposed method and some state-of-the-art works on the yeast dataset. Here, N/A means not available.

Model	Test set	SN (%)	PPV (%)	ACC (%)	MCC (%)
Proposed method	SVM	85.74 ± 0.94	93.84 ± 0.98	90.06 ± 0.64	82.03 ± 1.03
Guos’ work	ACC	89.93 ± 3.68	88.87 ± 6.16	89.33 ± 2.67	N/A
	AC	87.30 ± 4.68	87.82 ± 4.33	87.36 ± 1.38	N/A
Zhous’ work	SVM + LD	87.37 ± 0.22	89.50 ± 0.60	88.56 ± 0.33	77.15 ± 0.68
Yangs’ work	Cod1	75.81 ± 1.20	74.75 ± 1.23	75.08 ± 1.13	N/A
	Cod2	76.77 ± 0.69	82.17 ± 1.35	80.04 ± 1.06	N/A
	Cod3	78.14 ± 0.90	81.86 ± 0.99	80.41 ± 0.47	N/A
	Cod4	81.03 ± 1.74	90.24 ± 1.34	86.15 ± 1.17	N/A