Research Article
Lipid Emulsion Attenuates Acetylcholine-Induced Relaxation in Isolated Rat Aorta
Figure 2
(a) Effect of Lipofundin MCT/LCT (0.2%, ) on the calcium ionophore A23187 concentration-response curves in the endothelium-intact aorta. Data are the mean SD and are expressed as the percentage of maximal precontraction induced by 3 10−7 M phenylephrine. versus control. (b) Effect of Lipofundin MCT/LCT (0.2%, ) on acetylcholine concentration-response curves in endothelium-intact aorta pretreated with 10−2 M tiron. Data are the mean SD and are expressed as the percentage of maximal precontraction induced by 3 10−7 M phenylephrine. ED50: versus tiron (10−2 M) alone. Maximal relaxation: versus tiron (10−2 M) alone.
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