PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury

Table 2

Effect of WY-14643 on lipid peroxidation in steatotic livers subjected to ischemia-reperfusion.

MDA
Sham	IR	WY-14643 + IR
0,32 ± 0,07	1,22 ± 0,13	0,76 ± 0,17

Photometric analysis of malondialdehyde levels (MDA). Sham: anesthesia and laparotomy, IR: 60 min partial ischemia and 24 h of reperfusion, and WY-14643 + IR: iv administration of WY-14643 (10 mg/kg) 1 hour before IR. versus Sham; versus IR.