Effects of Sevoflurane and Propofol on Organ Blood Flow in Left Ventricular Assist Devices in Pigs

Table 2

Hemodynamic parameters in both groups (propofol and sevoflurane) at baseline and 30 minutes after implantation of a left ventricular assist device.

	Propofol; = 5	Sevoflurane; = 5	values
HR (beats/min)
Baseline	95 ± 4	89 ± 9	0.546
PS 30′	101 ± 6	101 ± 6	0.964
APm (mmHg)
Baseline	70 ± 3	65 ± 5	0.384
PS 30′	65 ± 8	74 ± 7	0.404
(mmHg)
Baseline	23 ± 2	25 ± 2	0.506
PS 30′	27 ± 1	33 ± 3	0.083
CVP (mmHg)
Baseline	15 ± 1	15 ± 1	0.856
PS 30′	14 ± 3	16 ± 2	0.584
CPP (mmHg)
Baseline	18 ± 1	18 ± 1	0.471
PS 30′	15 ± 0.5	19 ± 1	0.052
SVRI
Baseline	1583 ± 199	1368 ± 143	0.450
PS 30′	1128 ± 173	1433 ± 234	0.351
PVRI
Baseline	171 ± 65	159 ± 32	0.877
PS 30′	217 ± 37	339 ± 85	0.269
CO (L/min)
Baseline	2.4 ± 0.3	3 ± 0.3	0.185
PS 30′	2.5 ± 0.4	3.1 ± 0.4	0.347
SvO2 (%)
Baseline	77 ± 4	82 ± 3	0.429
PS 30′	82 ± 1	89 ± 3	0.150
(°C)
Baseline	35.1 ± 0.2	35.9 ± 0.3	0.080
PS 30′	33.9 ± 0.4	34.6 ± 0.4	0.332

Data are expressed as the mean ± standard error of the mean. HR: heart rate; AP_m: mean arterial blood pressure; : pulmonary artery mean pressure; CVP: central venous pressure; CPP: pulmonary capillary wedge pressure; SVRI: systemic vascular resistance index; PVRI: pulmonary vascular resistance index; CO: continuous cardiac output; SvO₂: mixed venous oxygen saturation; : temperature; PS: partial support.