|
Organism | Approach | Findings | References |
|
M. extorquens AM1 | Proteome | Identify a PhyR stress regulator during phyllosphere colonization using 2D analysis. | [59] |
M. extorquens AM1 | Proteome | Proteomic comparison under single carbon (methanol) and multicarbon (succinate) growth in a gel free quantitative proteomic assay. | [134] |
M. extorquens AM1 | Proteome | Cytosolic protein differentially modulated under single carbon (methanol) and multicarbon (succinate) growth. | [135] |
M. extorquens AM1 | Proteome | Compare wild type with M. extorquens AM1 lacking isocitrate lyase (the key enzyme in the glyoxylate cycle) during growth on acetate, which was replaced by ethylmalonyl-CoA pathway. | [138] |
M. extorquens DM4 | Proteome | Differential proteomic analysis of cultures grown with DCM and with methanol elucidates growth metabolism in the presence of DCM. | [26] |
M. extorquens CM4 | Proteome and genome | Comparison of growth with one-carbon substrates: chloromethane and methanol, reporting the genes required for chloromethane utilization. | [140] |
M. extorquens AM1 | Proteogenome | Refined the annotation of protein coding genes and discover genes in M. extorquens AM1 genome. | [132] |
M. extorquens AM1 | Metabolomic | Analyze the metabolites produced during single carbon (methanol) and multicarbon (succinate) growth, providing clues to new pathways that are specifically linked to C1 metabolism. | [136] |
M. extorquens AM1 | Metabolomic | Metabolites produced by M. extorquens AM1 grown on two carbon sources, ethylamine (C2) and succinate (C4) using LC-based and GC-based methods showing differences in in pathways linked to C2 and C4 metabolism. | [137] |
M. extorquens AM1 | Transcriptome | Validate a microarray plataform comparing genes expressed during single carbon (methanol) and multicarbon (succinate) growth, pointing candidate genes in C1 metabolism. | [133] |
M. extorquens AM1 | Transcriptome | Elucidates the regulation of general stress regulator (PhyR) using microarray. | [139] |
M. extorquens AM1 e DM4 | Genome comparison | Genome comparison of M. extorquens strain AM1 (reference strain) and the dichloromethane-degrading strain DM4 concluding that rearrangements and horizontal gene transfer resulted in a great genomic plasticity. | [128] |
Methylobacterium strains | Genome announcement | Six Methylobacterium strains adapted to different plant-associated niches and environmental: M. extorquens (PA1, CM4. BJ001), M. radiotolerans (JCM2831), M. nodulans (ORS2060), and Methylobacterium sp. 4-46 | [130] |
M. mesophilicum SR1.6/6 | Genome announcement | Endophytic bacterium isolated from a surface-sterilized Citrus sinensis. | [127] |
Methylobacterium sp. GXF4 | Genome announcement | A xylem-associated bacterium isolated from Vitis vinifera L. grapevine. | [43] |
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