Screening Active Compounds from Garcinia Species Native to China Reveals Novel Compounds Targeting the STAT/JAK Signaling Pathway

Table 2

The IC50s for GB32, GB39, and GB40 against the JAK1, JAK2, JAK3, and Tyk2 enzymes.

IC50 [M]	GB32	GB39	GB40
JAK1	>40	12.2 ± 0.3	14.2 ± 0.4
JAK2	37.3 ± 6.9	1.7 ± 0.1	1.4 ± 0.1
JAK3	17.5 ± 1.5	3.8 ± 0.3	3.2 ± 0.2
Tyk2	>40	13 ± 1.6	12.9 ± 0.9