Effects of Two Fullerene Derivatives on Monocytes and Macrophages

Table 1

Fullerene cytotoxicity on primary and stabilized cells of lymphoid and myeloid derivation.

	Cell lines			Primary cultures
	U937	U937_PMA	BJAB	Monocytes	MDM_LPS	Lymphocytes
Fullerene 1	27 μM	34 μM	40 μM	>>50 μM	>50 μM	>50 μM
Fullerene 2	17 μM	32 μM	24 μM	>>50 μM	>50 μM	>50 μM

Cells (10⁵/well) were treated in complete medium with fullerene 1 and fullerene 2 for 24 hr and then subjected to MTT test. IC₅₀ values were obtained (interpolation with GraphPad InStat) from data of repeated experiments; each of them are being with samples at least in triplicate.