Somatostatin Receptor Based Imaging and Radionuclide Therapy

Figure 5

camera imaging of mice injected with c-labeled SST analogs. Imaging position is shown in (a), with 3 representative images of mice at 3 minutes (b) and 3 hours (c) after intravenous injection. Circles in (c) indicate location of human A427 tumors injected 48 h earlier with Ad5-CMV-hSSTr2, and squares indicate human A427 tumors injected 48 h earlier with Ad5-CMV-LacZ. (d) Results of region of interest analyses [19]. A427 tumors: human non-small-cell lung cancer, hSSTr2 negative Ad5-CMV-LacZ: Ad encoding Escherichia coli β-galactosidase under control of the CMV promoter element.

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(b)

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