Coexpression Network Analysis of miRNA-142 Overexpression in Neuronal Cells

Figure 3

The miR-null coexpression network enriched with miRNA-mRNA seed sequence mapping. Node represents gene name and an edge between two nodes (genes) represents coexpression of the genes. Color of the node represents the miRNA seed sequence mapping onto the 3p UTR of a gene (mRNA). The “dark red” node represents exact miR-142-5p seed mapping, while the “pink” node represents inexact miR-142-5p seed mapping. Similarly, “dark green” node represents exact mapping of miR-142-3p seed and the “light green” node represents inexact mapping. The “blue” node represents genes with inexact mapping for both miR-142-3p and miR-142-5p seed sequences. No node was found to have exact mapping of both miR-142-5p and miR-142-3p.