Association between Micronutrient Levels and Chronic Spontaneous Urticaria
Table 1
Differences in micronutrient levels between SGH patients and the general UK population, aged 19 to 64 years.
CSU patients in SGH (mean ± SD)
Normal population in NDNS (mean ± SD)
P value
Vitamin D levels (nmol/L)
51.4 ± 27.03 ( = 225)
45.4 ± 24.84 ( = 1321)
0.001
Vitamin D levels (nmol/L), females
53.1 ± 27.51 ( = 163)
47.3 ± 25.61 ( = 770)
0.010
Vitamin D levels (nmol/L), males
46.8 ± 25.38 ( = 62)
43.5 ± 23.87 ( = 551)
0.306
Vitamin B12 levels (ng/L)
284 ± 108.4 ( = 176)
359 ± 131.2 ( = 1320)
<0.001
Vitamin B12 levels (ng/L), females
281 ± 113.8 ( = 133)
359 ± 132.2 ( = 768)
<0.001
Vitamin B12 levels (ng/L), males
295 ± 89.7 ( = 43)
359 ± 130.2 ( = 552)
0.002
Ferritin levels (ug/L)
61 ± 57.0 ( = 188)
97 ± 90.2 ( = 1329)
<0.001
Ferritin levels (ug/L), females
48 ± 44.4 ( = 140)
56 ± 53.6 ( = 775)
0.096
Ferritin levels (ug/L), males
101 ± 70.3 ( = 48)
140 ± 100.6 ( = 554)
0.009
Definition of micronutrient deficiency: vitamin D < 50 nmol/L; vitamin B12 < 130 ng/L; ferritin < 11 ug/L for females; ferritin < 24 ug/L for males. NDNS: the National Diet and Nutrition Survey; SGH: Southampton General Hospital.
