Review Article

Regulation of DEAH/RHA Helicases by G-Patch Proteins

Table 1

Summary of biological functions of DEAH/RHA helicases activated by a G-patch protein. The different biological processes, in which Prp43/DHX15 and Prp2/DHX16 and their activators are implied, are listed. The yeast orthologs are listed in parenthesis.

DEAH/RHAFunctionsProtein partner

DHX15 (Prp43)SplicingTFIP11  (Ntr1); RBM5
Ribosome
biogenesis
SQS1 (Pfa1);
PINX1 (Gno1)
?GPATCH2
Immunity?

DHX16 (Prp2)Splicing(Spp2)