Clinical Study
Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study
Table 1
Baseline characteristics in 157 patients with metastasesa.
| Characteristic | Preoperative zoledronic acid group (group A; ) | Control group (group B; ) | |
| Sex | | | 0.871 | Men | 48 | 46 | | Women | 33 | 30 | | Age (y) | | | 0.205 | Mean ± SD | 54.6 ± 10.1 | 52.5 ± 11.0 | | Range | 33–75 | 31–87 | | Primary tumor | | | 0.293 | Lung | 30 | 19 | | Liver | 11 | 19 | | Thyroid | 14 | 8 | | Breast | 7 | 10 | | Renal | 6 | 7 | | Prostate | 6 | 8 | | Other | 7 | 5 | | Preoperative Frankel score | | | 0.296 | A | 3 | 1 | | B | 6 | 4 | | C | 26 | 20 | | D | 36 | 46 | | E | 10 | 5 | | Number of spinal metastases | | | 0.508 | Single | 74 | 67 | | Multiple | 7 | 9 | | Complete arterial embolism | | | 0.588 | Yes | 61 | 60 | | No | 20 | 16 | | Tumor location | | | 0.605 | Cervical | 14 | 17 | | Thoracic | 35 | 34 | | Lumbar | 32 | 25 | |
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SD: standard deviation.
aThe Student’s -test was used for continuous variables, and chi-square analysis was used for categorical variables.
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