Clinical Study
Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study
Table 4
Comparison of intraoperative blood loss and surgical approach in 19 patients with multiple myeloma.
| Intraoperative blood loss | Preoperative zoledronic acid group (group C; ) | Control group (group D; ) | |
| Mean ± SD (volume per milliliter) | 1994 ± 810 | 3134 ± 795 | 0.007 | Range (volume per milliliter) | 890–3200 | 2200–4450 | | Distribution | | | 0.041 | 500–1000 mL | 2 | 0 | | 1001–2000 mL | 4 | 0 | | 2001–3000 mL | 3 | 5 | | ≥3001 mL | 1 | 4 | | Surgical approach | | | 0.510 | Anterior | 2 | 3 | | Posterior | 8 | 6 | | Combined | 0 | 0 | |
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