The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep

Figure 9

Chloracetatesterase enzyme histochemistry demonstrated (A)–(E) accumulation of erythrocytes (arrow) at implant interface of the different Mg screws ((A)-(B) diecasting, (C) milling, (D)-(E) coating) without any alterations between them. (F)–(I) At the postoperative follow-up times of 12 weeks (w) and (J)–(L) 1 year (y) no accumulation of erythrocytes was found. Infiltration of neutrophil granulocytes was not detected. Imp: empty space that is created by removing the implant before preparation of paraffin sections, gb: gas void, b: bone, epi: epiphyseal plate, bm: bone marrow, gt: granulation tissue, and cp: corrosion product.