The MicroRNA3686 Inhibits the Proliferation of Pancreas Carcinoma Cell Line by Targeting the Polo-Like Kinase 1

Figure 3

The microRNA3686 is able to inhibit cell proliferation and arrest cell cycle. (a) The cell proliferation assay for mir3686 mimic or scramble control transfected cells. The MTT cell proliferation kit was used to determine the cell proliferation in indicated time points; error bars represent standard errors of three repeated experiments. Significant differences between scramble or mir3686 transfected cells are shown by “.” (b) Flow cytometry based cell cycle analysis for PANC1 cell transfected with scramble control or mir3686 mimic transfected cell. (c) The quantification of cell cycle from flow cytometry data; three repeating experiments had been conducted for each group. Significant differences between scramble or mir3686 transfected cells are shown by “” ().