Review Article

Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

Table 1

Properties of polysaccharides commonly used for coating or encapsulation of MNPs.

PolysaccharideNatural sourceChargeFunctional
groups

AlginateDistributed widely in the cell walls of brown algaeNegativeOH
COOH

ChitosanFrom the exoskeletons of shrimp and other crustaceans treated with sodium hydroxidePositiveOH
NH2

DextranFirst discovered by Louis Pasteur as a microbial product in wineNeutralOH

Hyaluronic acidDistributed widely throughout connective, epithelial, and neural tissuesNegativeOH
COOH

HeparinExtracted from animal tissuesNegativeOH
OSO3H

MannanPlant polysaccharide a form of storage polysaccharideNeutralOH

PullulanProduced from starch by the fungus Aureobasidium pullulans NeutralOH

StarchProduced by most green plants to store energy NeutralOH