Research Article
Improved Diagnostic Multimodal Biomarkers for Alzheimer’s Disease and Mild Cognitive Impairment
Table 3
Model performance.
| Analysis | Cohort | Accuracy | Sensitivity | Specificity | AUC |
| HC-AD | Calibration set | 0.877 (0.792–0.948) | 0.849 (0.696–0.964) | 0.905 (0.75–1) | 0.945 (0.889–0.987) | Test set | 0.854 | 0.913 | 0.8 | 0.922 |
| HC-MCI | Calibration set | 0.802 (0.718–0.877) | 0.862 (0.75–0.957) | 0.704 (0.531–0.875) | 0.864 (0.789–0.934) | Test set | 0.785 | 0.805 | 0.75 | 0.841 |
| MCI-AD | Calibration set | 0.838 (0.781–0.892) | 0.476 (0.281–0.68) | 0.941 (0.88–0.989) | 0.838 (0.76–0.911) | Test set | 0.8 | 0.333 | 0.93 | 0.815 |
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Calibration set results represent the mean of the 1,000 bootstrap samples and the values in parenthesis represent the 95% confidence intervals.
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