Improved Diagnostic Multimodal Biomarkers for Alzheimer’s Disease and Mild Cognitive Impairment

Table 3

Model performance.

Analysis	Cohort	Accuracy	Sensitivity	Specificity	AUC
HC-AD	Calibration set	0.877 (0.792–0.948)	0.849 (0.696–0.964)	0.905 (0.75–1)	0.945 (0.889–0.987)
	Test set	0.854	0.913	0.8	0.922
HC-MCI	Calibration set	0.802 (0.718–0.877)	0.862 (0.75–0.957)	0.704 (0.531–0.875)	0.864 (0.789–0.934)
	Test set	0.785	0.805	0.75	0.841
MCI-AD	Calibration set	0.838 (0.781–0.892)	0.476 (0.281–0.68)	0.941 (0.88–0.989)	0.838 (0.76–0.911)
	Test set	0.8	0.333	0.93	0.815

Calibration set results represent the mean of the 1,000 bootstrap samples and the values in parenthesis represent the 95% confidence intervals.