Curcumin and Its Analogue Induce Apoptosis in Leukemia Cells and Have Additive Effects with Bortezomib in Cellular and Xenograft Models

Figure 1

Effect of curcumin (C) or C-150 treatments alone or in combination with bortezomib (BTZ) on cell viability. C-150 (0.3 μM) could potentiate the cytotoxic effect of 20 nM bortezomib at 50-fold lower concentration than curcumin (15 μM). Data represent total apoptotic cells (; , two-tailed Student’s -test).

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