Research Article
Curcumin and Its Analogue Induce Apoptosis in Leukemia Cells and Have Additive Effects with Bortezomib in Cellular and Xenograft Models
Table 3
In vitro effect of curcumin and C-150 on NF-κB signaling. Curcumin and its analogue C-150 alone or in coadministration with bortezomib decreased the activation of NF-κB pathway in a dose-dependent manner. Modest significant additive effect was recorded after coadministration of C-150 with bortezomib (: bortezomib versus combination; : curcumin or C-150 versus combination; two-tailed Student’s -test).
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