Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight

Table 2

Effects of spaceflight on yeast genome responses identified with the homozygous deletion series.

General pathway	GO biological process
RNA metabolism and catabolism	(i) Ribosome biogenesis; (ii) Regulation of ribosomal protein transcription; (iii) Cytoplasmic RNA translation; (iv) rRNA processing; (v) tRNA modification; (vi) mRNA decay
DNA integrity	(i) DNA repair; (ii) Recombination and replication; (iii) Chromatin remodeling; (iv) Mitochondrial maintenance; (v) Proper protein localization to the mitochondria