Translationally Controlled Tumor Protein in Prostatic Adenocarcinoma: Correlation with Tumor Grading and Treatment-Related Changes

Figure 2

TCTP protein expression in untreated patients. TCTP staining increases as Gleason pattern progresses from Gleason pattern 3 (a) to Gleason pattern 4 (b) to 5 (c); in the latter isolated neoplastic cells strongly express the protein (-test, ). High positivity is also present in associated-cancer HGPIN ((d), arrow) in respect to the non-neoplastic tissue. (Original Magnification, O.M.: (a)–(d), 10x).

(a)

(b)

(c)

(d)