Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure

Table 2

Characteristics of CHF patients and control participants.

	CHF ()	Control ()	P
Age (years)	62.7 ± 12.3	62.6 ± 8.3	0.909
Male	207 (62.2%)	212 (59.9%)	0.584
BMI (kg/m^2)	24.3 ± 2.7	23.9 ± 2.8	0.076
Hypertension	202 (60.7%)	93 (26.3%)	<0.001
Dyslipidemia	119 (35.7%)	70 (19.8%)	<0.001
Diabetes	106 (31.8%)	33 (9.3%)	<0.001
Smokers	125 (37.5%)	67 (18.9%)	<0.001
LVEF (%)	33.3 ± 7.0	65.2 ± 6.1	<0.001
Etiology
Ischemic	180 (54.1%)	—
Nonischemic	153 (45.9%)	—
NYHA class
II	98 (29.4%)	—
III	130 (39.0%)	—
IV	105 (31.5%)	—

BMI: body mass index, LVEF: left ventricular ejection fraction, and NYHA: New York Heart Association.
P values were calculated by Student’s t-tests.
P values were calculated from two-sided chi-square test.