| | Drugs | Direction | Genes |
| | Piperlongumine | Decrease | CLEC5A, TNFAIP6, FCGR1B, C3, NEIL3, RNASE6, C3AR1, SAMSN1, CAPG, CD86, TREM1, IRF8, EVI2A, PBK, FCGR2A, RGS13, KCNN4, GPR183, TLR2, GINS2, CLEC7A, RRM2, RGS1, CD300A, CD14, CTSC, TMEM158, CDCA3, NCF2, SYK, IL1B, GINS1, SLC43A3, PSRC1, MYC, FILIP1L, MYO1F, PLAUR, PFKP, CCR1, HELLS, PLAU, PTPRE, MNDA, TNFAIP8, MAD2L1, CYP1B1, RASSF2, GALNT7, ECT2, CD300C, CDC45 | | Increase | HPS5, EAF2, RND1 |
| | 15d-PGJ2 | Decrease | MLPH, CXCL6, TOP2A, LPAR1, GPR39, DLGAP5, HMGA2, SCG5, CXCL1, PTX3, INHBA, TNFRSF11A, COL5A2, TENM4, ASPM, KIF18B, CENPF, KIF20A, IL33, SYTL2, CCNB2, CCNA1, HJURP, CDC20, CDH11, LMNB1, NCAPH, MKI67, CDCA3, FST, TTK, NDP, GINS1, MTCL1, PSRC1, NEK2, HAS2, CDCA8, NPM3, ETV1, KIF2C, FAM110B, PRSS23, CDK1, PLAU, MALL, P2RY6, AURKB, BNC2, FJX1, CCNB1, TROAP, IGSF3, CYP1B1, ECT2, TK1, IRS1 | | Increase | PRKCE, SLC16A10, ERVMER34-1, EAF2, RND1, EGF, ZNF804A, SERPINI2 |
| | Vorinostat | Decrease | CLEC5A, PLA2G7, CTSG, FCGR1A, FCGR1B, VCAN, LAIR1, BCAT1, HP, PTAFR, C3AR1, ADORA3, LILRB4, HGF, IGSF6, CCR2, NCF4, MS4A6A, CD33, MMP9, GNA15, EVI2A, TLR1, ATP8B4, CACNA2D3, LILRB1, KCNN4, GPR183, ANXA3, TLR2, CLEC7A, RRM2, RGS1, LMNB1, NINJ2, CD300A, CSF2RA, NCAPH, CD14, INHBE, LILRA2, SIGLEC9, LAT2, SYK, SLC38A1, SLC43A3, MYC, GLIPR1, PTENP1, MYO1F, PSTPIP1, PLAUR, CCR1, PLAU, DOK3, SELPLG, SASH3, P2RY6, VAV1, PTPRE, MNDA, SPI1, DEF6, CYBRD1, CXorf21, CYP1B1, RASSF2, DOK2 | | Increase | ACOX2, EXPH5, PRKAR2B, GDPD3, MLXIPL, RND1, CTSV |
| | Trichostatin A | Decrease | CLEC5A, FCGR1B, VCAN, LAIR1, RNASE6, C3AR1, HGF, IGSF6, NCF4, MS4A6A, SLC7A11, EVI2A, KIF20A, ATP8B4, CACNA2D3, RGS13, KCNN4, GPR183, ANXA3, CLEC7A, RRM2, RGS1, LMNB1, CD300A, CD14, INHBE, PYCARD, LILRA2, SYK, SLC38A1, SLC43A3, PIK3CG, MYC, FILIP1L, PSTPIP1, PLAUR, FOXM1, PLAU, SASH3, P2RY6, VAV1, MNDA, SPI1, CSF3R, CYBRD1, CXorf21, MICAL1, CYP1B1, RCC1, P2RX1, ARRB2, RASSF2, GALNT7, DOK2, FAM129A | | Increase | PRKAR2B, CTNNBIP1, RND1, CTSV |
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